Protein and nucleic acid relationship tips

Peptide nucleic acid - Wikipedia

protein and nucleic acid relationship tips

Different types of proteins. The structure and properties of amino acids. Formation of peptide bonds. Bacterial cells have complex macromolecules built from simple molecules. In this lesson, we will look at the major elements in the building. This progression from DNA to RNA to protein is called the “central dogma” of . strands of a DNA double helix have a very predictable relationship to each other.

A gene is a basic unit of heredity in a living organism that normally resides in long strands of DNA called chromosomes. Genes are coded instructions that decide what the organism is like, how it behaves in its environment and how it survives.

A gene consists of a long combination of four different nucleotide bases namely adenine, cytosine, guanine and thymine. All living things depend on genes as they specify all proteins and functional RNA chains. Proteins are large, complex molecules that play many critical roles in the body. They are necessary for building the structural components of the human body, such as muscles and organs.

Proteins also determine how the organism looks, how well its body metabolises food or fights infection and sometimes even how it behaves. Proteins are chains of chemical building blocks called amino acids. If you look closely, you will start to make out some major cell structures - maybe a flagella, a cell wall, a cell membrane, some DNA, and even some ribosomes.

protein and nucleic acid relationship tips

Zoom in a little bit more and you start to see individual proteins floating around inside the cell catalyzing chemical reactions. Many of these components of the cell are made up of macromolecules, which simply means large molecules formed by linking together small molecules. In this lesson, we will discuss the structure of these macromolecules and break them down into their individual units, all the way down to individual atoms.

protein and nucleic acid relationship tips

To keep track of the elemental building blocks for our macromolecules, we will use this handy table and fill it in as we go. Proteins Proteins play important roles within a cell.

protein and nucleic acid relationship tips

Some make up the structure of cell components, like a flagella or a pilus, and many play the role of enzymes to catalyze the reactions necessary for life.

Let's take a look at a protein.

Nucleic Acids: Function & Structure - Video & Lesson Transcript |

As you can see, they are complicated structures that can be made up of hundreds to thousands of individual units, called amino acids, all linked up in a chain and then folded up like origami into complicated shapes. The structure may seem complex, but all proteins are actually made up of around 21 different amino acids, just in many different combinations. Every amino acid has the basic structure shown here consisting of carbon, hydrogen, oxygen, and nitrogen. RNA nucleotides may also bear adenine, guanine and cytosine bases, but instead of thymine they have another pyrimidine base called uracil U.

Uncovering the Relationship Between Genes and Proteins - ATA Scientific

As shown in the figure above, each base has a unique structure, with its own set of functional groups attached to the ring structure. In molecular biology shorthand, the nitrogenous bases are often just referred to by their one-letter symbols, A, T, G, C, and U. These two are very similar in structure, with just one difference: Polynucleotide chains A consequence of the structure of nucleotides is that a polynucleotide chain has directionality — that is, it has two ends that are different from each other.

DNA sequences are usually written in the 5' to 3' direction, meaning that the nucleotide at the 5' end comes first and the nucleotide at the 3' end comes last. This makes a chain with each sugar joined to its neighbors by a set of bonds called a phosphodiester linkage.

protein and nucleic acid relationship tips

Properties of DNA Deoxyribonucleic acid, or DNA, chains are typically found in a double helix, a structure in which two matching complementary chains are stuck together, as shown in the diagram at left. The sugars and phosphates lie on the outside of the helix, forming the backbone of the DNA; this portion of the molecule is sometimes called the sugar-phosphate backbone.

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  • Introduction to proteins and amino acids
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The nitrogenous bases extend into the interior, like the steps of a staircase, in pairs; the bases of a pair are bound to each other by hydrogen bonds. Structural model of a DNA double helix. This is referred to as antiparallel orientation and is important for the copying of DNA.

Why Humans Need Nucleic Acids

So, can any two bases decide to get together and form a pair in the double helix? The answer is a definite no. Because of the sizes and functional groups of the bases, base pairing is highly specific: